The Carabao Cup final between Tottenham and Manchester City will have 8,000 fans in attendance after it was confirmed as a pilot event to test the return of big crowds.
A proportion of tickets will be made available to both clubs for the game at Wembley Stadium on 25 April.
Rick Parry, chair of the English Football League (EFL), said it was an “important milestone”.
On 18 April, the FA Cup semi-final between Leicester City and Southampton will have 4,000 fans while the final on 15 May will welcome 21,000 spectators.
Those games will also trial a Covid passport scheme, where passes would show if a person had been vaccinated, had a recent negative test, or natural immunity.