COVID-19: Strengthening vaccine production in Nigeria

At a critical moment in the battle against the resurgence of the second wave of , it is clear that is still relying on vaccines imported from the western world to wade off the deadly pandemic.

This is evident in the struggle to import the vaccines from abroad to stem the spike of the . Undoubtedly, this is a time-consuming and high-priced enterprise. Apart from the non-pharmaceutical measures to curb the spread of , the government should systematically rebuild the capacity of the domestic research institutes to produce vaccines against future outbreaks.

Despite its ruthless augury, the pandemic presents a rare opportunity for to resuscitate its decayed health system, including domestic production of drugs and vaccines. As of January 22, had recorded 116,655 cases with 1,485 deaths. It recorded 1,964 cases on January 21. Already, hospitals are running short of oxygen for treatment of patients, particularly in Lagos, the epicentre. Thus, the federal and state governments should seize the opportunity to reverse ’s unwholesome dependence on import of health materials and and its over-reliance on medical aid for survival.

Looking at its robust crop of health professionals and researchers, several things are awfully wrong with the domestic production of vaccines. There is high contempt for and neglect of science and technology in the country. Although the surfaced in December 2019 in Wuhan, China – that gave ample time to make amends – the federal government budgeted just N5.4 billion in the 2021 Appropriation Act for three leading public vaccine institutes. At N4.23 billion, the Nigerian Institute of Medical Research got the highest, followed by N1.28 billion for the National Institute for Pharmaceutical Research and and N329.48 million for the National Arbovirus and Vectors Research Centre. It just released additional N10 billion for local vaccine production. Experts say an estimated 14 billion doses of vaccine would be needed globally to stop the pandemic. But countries with the capacity for research and and the competencies for vaccine production are taking care of their citizens first.

According to NIPRD, it was necessary to suspend research into major projects for the treatment of the last year because of receding funding. Oyewale Tomori, the immediate past president of the Nigerian Academy of Science, decried, “It is a minus for us that while India, China, Iran and many others, probably even some African countries, are doing their vaccines, we are waiting for some donors to send to us.”

In this regard, has joined 53 other countries in COVAX, a global initiative which is a collaboration of the Coalition for Epidemic Preparedness Innovations, the Vaccine Alliance and the World Health Organisation to channel 270 million doses of the vaccine to African Union member-states.

Recognising the importance of the vaccine, the federal government has earmarked N400 billion for the procurement of various types. To meet its target of vaccinating at least 20 percent of people in poor countries next year, COVAX says it needs $4.9 billion in addition to the $2.1 billion it has already raised.

As a consolation, Ekiti state , Kayode Fayemi, says is among the 12 African countries that will benefit from the first shipment of the vaccine. The challenge is that the shipment will arrive in February. At the rate the infection is ballooning, much damage could have been done by then. In addition, the government says it has provided N6.45 billion to establish oxygen production plants in 38 sites nationwide to combat the rising incidence of the pandemic.

According to Our World in Data figures, Israel had vaccinated 38 per cent of its by January 21, the highest percentage globally. The United Arab Emirates is second with a rate of 22.7 per cent; Bahrain at 8.5 per cent; the at 8.0 per cent and the US at 5.3 per cent are also making progress. Nigeria hopes to vaccinate 40 per cent of the by year end. Even at that, it appears far-fetched that the country will be able to procure the number of vaccines to meet the target. It is projected that lower income countries may be waiting until 2023 or 2024 before gaining widespread access to vaccines.

In the absence of local capacity, there is also the fear that substandard and falsified vaccines may enter the supply-chain, diminishing trust in vaccines and health systems.

However, reports say some middle-income countries, particularly India, Argentina and Mexico, have sufficient production capacity to be partly indispensable. These countries have strategic leverage to get vaccines because of their own vaccine manufacturing capacity.

Accordingly, it is said that the Serum Institute of India, a privately owned pharmaceutical company, is manufacturing large quantities of the of Oxford/AstraZeneca and Novavax COVID-19 vaccines primarily first for the Indian .

Once again, Nigeria is lagging behind. The country established a centre for the local production of vaccines at the Federal Vaccine Production Laboratory, Lagos around 1940. It used the vaccines produced there to combat many outbreaks, including the yellow fever incidence in the mid-80s. But the system broke down in 1991 when the plant was reportedly shut down for upgrading. Nothing significant has occurred there since. In turn, Nigeria looks to donors to vaccinate its growing against diseases like polio, meningitis and viral haemorrhagic fevers. Some of these vaccines have to be stored at minus zero degree temperatures. This puts Nigeria and its estimated 206 million citizens at a gaping disadvantage.

It is argued that developing the fledgling vaccine production industry will also help countries prepare for greater self-sufficiency in meeting their growing vaccine needs and prevent future vaccine access crises when the next pandemic hits.

The federal government should revive the research institutes, especially as the WHO reckons that the world is not too far away from future outbreaks of diseases. As the country strives to secure COVID-19 vaccines from abroad, efforts and funding should be improved in the local production of vaccines for domestic use.

Muhammad writes from Mass Communication Department, Abubakar Tatari Ali Polytechnic, Bauchi.

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