Tottenham get their FA Cup campaign underway when they host Portsmouth at White Hart Lane.
The Lilywhites come into this game after a much needed victory over Crystal Palace, following a surprise 2-0 defeat to Aston Villa.
Antonio Conte’s men will be heavy favorites against the League one side who have gone nine successive games without a win and have failed to score in three of their last four games.
Spurs have won 10 and drawn seven out of 21 matches against Pompey, though the former Premier League outfit won their last encounter 13 years ago in the FA Cup Semi Final.
Spurs though should have what it takes to secure passage to the next round.
Wolves make the tough trip to Anfield to face Liverpool as Julen Lopetegui looks to guide his side to an upset.
Lopetegui picked up back to back wins over Gillingham and Everton before falling to a narrow 1-0 defeat to Man United.
A 1-1 draw against Aston Villa in the League followed, and now they match up against an inconsistent Reds side who will still have defeat to Brentford fresh on their minds.
Liverpool though will see this as a match to return to winning ways, having won their last seven matches and winning 31 of 46 matches against the Wanderers. Still, Jurgen Klopp will be hoping his side don’t fall victim to the upsets of the FA Cup.
Newcastle will travel to the Hillsborough Stadium to take on an impressive Sheffield Wednesday. The Owls have been solid in League one, claiming their third win in a row in a 5-0 thrashing of Morecambe.
They have conceded just one goal in their last four League one outings, although they are coming up against the team with the best defensive record in the Premier League this season, conceding just 11 goals in 18 games.
They are yet to concede a goal in any of their last four games after the World Cup break, though they will be wary of the fact that Sheffield have won their last three encounters. Their away record against the Owls doesn’t make for impressive reading either, and the Toon Army will be desperate to improve this come matchday.
Man City will be eyeing back to back wins against Chelsea at the Etihad Stadium.
The Citizens drew first blood in a 1-0 victory at Stamford Bridge in the League, and will now look to heap more misery on the Blues by securing FA Cup progression.
Manager Graham Potter is running out of time to prove himself at the helm, and defeat here could put an early end to a rather unfortunate spell at the Bridge.
