Liverpool will entertain West Ham at Anfield.
The Reds come into this on the back of a 2-0 win over Midtjylland in midweek, and will look to make it back to back league wins having beaten Sheffield United last time. West Ham will have it all to do to get something out of this one.
They put in a solid shift at the Olympic Stadium to pick up a 1-1 draw over Man City, but Liverpool will surely be too strong for them in the end.
Chelsea will be looking for their first win in three games when they travel to take on Burnley at Turf Moor.
They take on a Burnley side who have lost four out of five games so far this season, and will be hot favorites to pick up the three points.
Manchester City will look to end their poor league form when they tackle Sheffield United at Bramall Lane.
The Citizens have picked up just eight points from a possible 15 and look out of the running for the title already. Sheffield on the other hand have been in even worse form themselves.
They have lost five of their six matches so far, and this looks like the perfect opportunity for Guardiola’s men to build some momentum.
On Sunday, Manchester United will host Arsenal in what will be the match of the weekend.
Both teams haven’t had the starts to the season that they would have wanted, which makes this fixture all the more important. United have started to show signs of resurgence though.
They come into this game on the back of a resounding 5-0 thrashing of RB Leipzig in the Champions League.
They have now won back to back games in Europe’s elite competition, and will now look to translate that form into domestic dominance. Arsenal on the other hand disappointed in a 1-0 loss to Leicester at the Emirates.
The Gunners are however unbeaten in their last three games against the Red Devils, and they will do very well to use that to their advantage.
Tottenham will take on Brighton at White Hart Lane. The Lilywhites suffered a first defeat in six games across all competitions when they were beaten 1-0 by Royal Antwerp on Thursday.
With key players such as Harry Kane and Heung Min Son returning to the starting line up, Jose Mourinho’s men are certain to get the three points.
Everton will look to shake off their first defeat of the season when they travel to face Newcastle at the Sports Direct Arena.
The Toffees were stunned 2-0 by Southampton last time out and had defender Lucas Digne sent off as well.
His suspension has since been reduced to one match from three, and manager Carlo Ancelotti will be hoping his side don’t slip up again. Newcastle are 14th on the log with just two wins to their name all season.
They played out a 1-1 draw with Wolves last time out and will look to build on that performance against the league leaders.
Aston Villa will host Southampton at Villa Park as they aim to avoid back to back defeats.
The Villains had won their opening four matches of the season but were then stunned by Leicester in what was in the end a comfortable victory for Marcelo Bielsa’s men.
Southampton inflicted a first defeat of the season on Everton, keeping a clean sheet in the process, and will now go in search of consecutive wins against the top two.